| Final 19:25 | time | gap | L | React. | Butter | Back | Breast | | 1. Caitlin Leverenz |  USA | 2:10.51 | PR | 4 | 0.82 | 28.14s | 1. | 1:01.19 | 1. | 1:38.50 | 1. | | 2. Meghan Small | USA | 2:11.26 | 0.75 | 3 | 0.77 | 28.58s | 2. | 1:01.81 | 2. | 1:40.02 | 2. | | 3. Sydney Pickrem |  CAN | 2:11.29 | 0.78 | 5 | 0.77 | 29.01s | 5. | 1:01.95 | 3. | 1:40.04 | 3. | | 4. Joanna Maranhao |  BRA | 2:12.39 | 1.88 | 7 | 0.77 | 28.87s | 3. | 1:02.23 | 4. | 1:41.88 | 5. | | 5. Erika Seltenreich-Hodgson | CAN | 2:14.06 | 3.55 | 6 | 0.73 | 29.05s | 6. | 1:02.59 | 5. | 1:41.18 | 4. | | 6. Virginia Bardach |  ARG | 2:15.45 | 4.94 | 1 | 0.81 | 29.09s | 7. | 1:04.27 | 6. | 1:43.35 | 6. | | 7. Gabrielle Goncalves | BRA | 2:17.02 | 6.51 | 8 | 0.71 | 29.78s | 8. | 1:05.37 | 7. | 1:45.57 | 8. | | 8. Alia Atkinson |  JAM | 2:18.02 | 7.51 | 2 | 0.72 | 28.98s | 4. | 1:05.48 | 8. | 1:44.44 | 7. |
| World Record: Ariana Kukors (USA) 2:06.15, Roma (ITA), 27.07.2009. | | Pan American Games Record: Jukia Smith (USA) 2:13.07, Rio de Janeiro (BRA), 20.07.2007. | | Qualification times. Standard A: 2:19.49, Standard B: 2:27.86. |
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| Final B 19:18 | time | gap | L | React. | Butter | Back | Breast | | 9. Florencia Perotti | ARG | 2:17.65 | | 4 | 0.86 | 30.30s | 2. | 1:03.83s | 2. | 1:45.35 | 1. | | 10.Mckenna De Bever |  PER | 2:18.49 | 0.84 | 3 | 0.75 | 28.97s | 1. | 1:03.64s | 1. | 1:45.66 | 2. | | 11.Arantxa Medina |  MEX | 2:18.82 | 1.17 | 5 | 0.73 | 30.49s | 4. | 1:06.73s | 4. | 1:46.37 | 3. | | 12.Mercedes Toledo |  VEN | 2:22.06 | 4.41 | 6 | 0.71 | 30.36s | 3. | 1:09.25s | 6. | 1:49.70 | 4. | | 13.Lara Butler |  CAY | 2:24.64 | 6.99 | 7 | 0.79 | 30.76s | 6. | 1:06.74s | 5. | 1:50.69 | 6. | | 14.Karen Vilorio |  HON | 2:24.72 | 7.07 | 2 | 0.74 | 30.62s | 5. | 1:06.11s | 3. | 1:50.13 | 5. | | -. Lisa Blackburn |  BER | DNS | | 1 | | | | | | |
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Heats - Saturday 18.07 10:16 | | First 8 to Final. Next 8 to Final B. |
| Ranking | time | gap | L | React. | Butter | Back | Breast | .Heat | | 1. Caitlin Leverenz | USA | 2:11.04 | PR | 4 | 0.76 | 28.45s | 1. | 1:02.38 | 1. | 1:39.83 | 1. | Heat 3 | | 2. Sydney Pickrem | CAN | 2:11.16 | 0.12 | 5 | 0.76 | 29.12s | 2. | 1:02.38 | 1. | 1:40.35 | 2. | Heat 3 | | 3. Meghan Small | USA | 2:13.90 | 2.86 | 4 | 0.83 | 28.72s | 1. | 1:02.91 | 1. | 1:42.19 | 1. | Heat 1 | | 4. Erika Seltenreich-Hodgson | CAN | 2:14.02 | 2.98 | 4 | 0.76 | 29.31s | 3. | 1:02.94 | 1. | 1:41.63 | 1. | Heat 2 | | 5. Alia Atkinson | JAM | 2:15.16 | 4.12 | 3 | 0.75 | 28.95s | 1. | 1:04.50 | 3. | 1:43.23 | 2. | Heat 2 | | 6. Joanna Maranhao | BRA | 2:15.32 | 4.28 | 5 | 0.82 | 29.17s | 2. | 1:03.47 | 2. | 1:43.87 | 3. | Heat 2 | | 7. Virginia Bardach | ARG | 2:16.86 | 5.82 | 5 | 0.82 | 29.33s | 2. | 1:04.61 | 2. | 1:44.02 | 2. | Heat 1 | | 8. Gabrielle Goncalves | BRA | 2:17.67 | 6.63 | 3 | 0.70 | 30.07s | 3. | 1:05.75 | 5. | 1:46.37 | 4. | Heat 3 | | to Final B | | 9. Florencia Perotti | ARG | 2:18.95 | 7.91 | 6 | 0.79 | 30.21s | 4. | 1:04.00 | 3. | 1:45.52 | 3. | Heat 3 | | 10.Arantxa Medina | MEX | 2:19.26 | 8.22 | 3 | 0.74 | 30.71s | 3. | 1:07.62 | 4. | 1:47.09 | 3. | Heat 1 | | 11.Mckenna De Bever | PER | 2:21.65 | 10.61 | 6 | 0.74 | 29.38s | 4. | 1:04.60 | 4. | 1:48.37 | 4. | Heat 2 | | 12.Mercedes Toledo | VEN | 2:25.24 | 14.20 | 2 | 0.78 | 30.37s | 5. | 1:09.30 | 5. | 1:50.96 | 5. | Heat 2 | | 13.Karen Vilorio | HON | 2:25.87 | 14.83 | 7 | 0.73 | 30.35s | 5. | 1:05.50 | 4. | 1:49.83 | 5. | Heat 3 | | 14.Lara Butler | CAY | 2:26.50 | 15.46 | 2 | 0.77 | 30.94s | 4. | 1:07.10 | 3. | 1:51.62 | 4. | Heat 1 | | 15.Lisa Blackburn | BER | 2:29.04 | 18.00 | 7 | 0.77 | 30.77s | 6. | 1:11.14 | 6. | 1:53.95 | 6. | Heat 2 | | eliminated | | -. Esther Gonzalez | MEX | DNS | | 6 | | | | | | | | Heat 1 | | -. Barbara Caraballo |  PUR | DNS | | 2 | | | | | | | | Heat 3 |
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| Swimmer | Q. time | Birth | | Caitlin Leverenz | USA | 2:10.67 | 26 FEB 1991 | | Erika Seltenreich-Hodgson | CAN | 2:11.76 | 24 APR 1995 | | Meghan Small | USA | 2:11.83 | 25 MAY 1998 | | Sydney Pickrem | CAN | 2:11.90 | 21 MAY 1997 | | Joanna Maranhao | BRA | 2:12.78 | 29 APR 1987 | | Virginia Bardach | ARG | 2:15.56 | 03 APR 1992 | | Gabrielle Goncalves | BRA | 2:17.05 | 19 JUL 1998 | | Alia Atkinson | JAM | 2:17.28 | 11 DEC 1988 | | Arantxa Medina | MEX | 2:17.80 | 03 AUG 1994 | | Florencia Perotti | ARG | 2:18.30 | 24 SEP 1992 | | Mckenna De Bever | PER | 2:18.30 | 05 JUN 1996 | | Esther Gonzalez | MEX | 2:18.92 | 26 JUN 1995 | | Standard A: 2:19.49 | | Barbara Caraballo | PUR | 2:20.88 | 15 SEP 1995 | | Mercedes Toledo | VEN | 2:22.53 | 17 MAY 1989 | | Lara Butler | CAY | 2:24.43 | 02 OCT 1994 | | Karen Vilorio | HON | 2:26.01 | 27 MAY 1993 | | Standard B: 2:27.86 | | Lisa Blackburn | BER | 2:29.60 | 19 NOV 1971 |
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